Revolutionary RNA-based biopesticide technology delivers 98% mortality of Colorado potato beetle in independent test

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Potato leaves protected by RenBio RNAi yeast against Colorado potato Beetles

Potato leaves protected by RenBio RNAi yeast against Colorado potato Beetles

September 30, 2021

Renaissance BioScience Corp., a leading global bioengineering company, is pleased to announce that an independent test of its environmentally safe, RNA-based biopesticide technology conducted on Colorado potato beetle (CPB) larvae resulted in 98.3% mortality and greatly reduced the amount of plant damage caused by the beetle.

The proof-of-concept test, conducted by a leading international agriculture consultancy with expertise in pesticide evaluation, applied Renaissance’s proprietary yeast-based RNA interference technology that is designed to precisely target and turn off a specific Colorado potato beetle gene. This, in turn, resulted in high Colorado potato beetlemortality and protected the potato plant.

A key characteristic and industrial benefit of the Renaissance novel proprietary RNA production and oral delivery platform technology is that it’s possible to include multiple different gene targets in each cell of the delivery system, thereby greatly reducing or eliminating the potential for Colorado potato beetle to develop resistance to this innovative biopesticide.
 

Potato leaves decimated by Colorado potato Beetle Larvae

Potato leaves decimated by Colorado potato Beetle Larvae

Renaissance BioScience CEO Dr. John Husnik:
 
"These are very promising results clearly showing that Renaissance’s environmentally safe technology protected the potato plant from the Colorado potato beetle. We still have work to do but these findings confirm the potential for our technology for crop protection."

"Given that the large-scale, low-cost production of yeast is already readily available from well-established global yeast companies, our focus now is maximizing effectiveness through further laboratory tests and field trials and organizing appropriate commercial partners for the next phases of product development."

"Renaissance’s RNA production and oral delivery platform technology is not only potentially efficacious as a biopesticide against a wide variety of different pests but also has significant promising applications in human and animal healthcare, including aquaculture."

"Yeast has been an amazing natural workhorse for human civilization for thousands of years, and we are applying it to develop many new exciting applications in environmentally safe biopesticides and biotherapeutics for the future."